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KMID : 0880520150510010039
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Chonnam Medical Journal
2015 Volume.51 No. 1 p.39 ~ p.42
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IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor
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Han Song-Yi
Lee Seung-Ik
Lee Yeon-Hee
Kim Ae-Jin
Lim Hye-Jin
Ro Han
Chang Jae-Hyun
Lee Hyun-Hee
Jung Ji-Yong
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Abstract
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Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.
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KEYWORD
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Immunoglobulin G, Sclerosis, Kidney
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